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抗BCL2L1抗體(anti-BCL2L1antibody)
抗BCL2L1抗體(anti-BCL2L1antibody)
產(chǎn)品價(jià)格:¥1900.00(人民幣)
  • 規(guī)格:完善
  • 發(fā)貨地:湖北武漢市
  • 品牌:
  • 最小起訂量:1
  • 免費(fèi)會(huì)員
    會(huì)員級(jí)別:試用會(huì)員
    認(rèn)證類型:企業(yè)認(rèn)證
    企業(yè)證件:通過(guò)認(rèn)證

    商鋪名稱:武漢菲恩生物科技有限公司

    聯(lián)系人:王先生(先生)

    聯(lián)系手機(jī):

    固定電話:

    企業(yè)郵箱:3495998903@qq.com

    聯(lián)系地址:武漢市江夏區(qū)高新大道818號(hào)高科醫(yī)療器械園B9棟

    郵編:430206

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    商品詳情
      產(chǎn)品參數(shù)
      品牌菲恩生物
      適用范圍僅供科研使用
      規(guī)格100μg
      加工定制
      驗(yàn)證應(yīng)用ELISA
      IHC
      IP
      IF
      WB
      宿主
      適應(yīng)種屬人源,銷售
      可售賣地全國(guó)
      材質(zhì)液體

        名稱:抗BCL2L1抗體(anti-BCL2L1 antibody)

        貨號(hào):FNab00842

        適應(yīng)種屬:人源,小鼠

        規(guī)格:100ug(微克)

        狀態(tài):液體

        純化方法:免疫親和純化

        純度:經(jīng)sds-page分析,純度大于95

        宿主:兔

        亞型:IgG

        存儲(chǔ):用添加了0.02疊氮化鈉和50甘油的pbs溶解,ph值7.3,可在-20℃下保存12個(gè)月(避免反復(fù)凍融)

        免疫原:BCL2-like 1

        免疫原別稱:BCL2L, BCLX

        分子量:30 kDa

        驗(yàn)證應(yīng)用:ELISA, IHC, IP, IF, WB

        建議稀釋比例:WB: 1:1000-1:6000; IP: 1:500-1:3000; IHC: 1:50-1:500; IF: 1:50-1:500

        克隆性:多克隆

        UniProt ID:Q07817

        背景介紹:Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel(VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. May attenuate inflammation impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785). Isoform Bcl-X(S) promotes apoptosis。

        Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab00842(BCL2L1 antibody) at dilution of 1:100。

        IP result of anti-BCL2L1(IP:FNab00842, 3ug; Detection:FNab00842 1:500) with K-562 cells lysate 8000 ug。

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